If you’re trying to conceive, especially after 35, you might be wondering: What more can I do to improve my chances?
I asked myself the same question when I started my fertility journey.
Like many women, I knew that age could affect egg quality and hormone balance, but I also believed that the right nutrients could support my reproductive health.
After lots of research, consultations with my doctor, and trial and error, I found a handful of science-backed supplements that I truly believe made a difference in my ability to conceive.
Improving overall health and egg quality can improve success whether you are TTC naturally or with IVF!
Today, I’m sharing the supplements that helped me get pregnant naturally over 35—in the hopes that they might help you, too! 💕
1. CoQ10 (Ubiquinol) – For Egg Quality & Cellular Energy
This was the #1 supplement my fertility doctor recommended to me. CoQ10 (specifically the Ubiquinol form) is a powerful antioxidant that helps:
✅ Improve egg quality by protecting against oxidative stress
✅ Support mitochondrial function (which gives eggs the energy needed for fertilization)
✅ Slow down egg aging
💡 What the science says:
Research shows that CoQ10 supplementation improves egg quality and fertility outcomes in women over 35.
🔹 My dosage: 200–300mg of Ubiquinol daily
2. Myo-Inositol – For Hormone Balance & Ovulation
I was experiencing short cycles (acupuncture helped me a lot with this!) and suspected some insulin resistance, so I started taking Myo-Inositol.
✨ Benefits for fertility:
✅ Regulates insulin levels, which helps balance hormones
✅ Supports ovulation & egg quality
✅ May help prevent miscarriage
💡 What the science says:
Studies show that Myo-Inositol can restore ovulation in women with irregular cycles and improve egg quality in IVF patients.
🔹 My dosage: 2000mg Myo-Inositol
3. Omega-3 Fish Oil – For Hormone Health & Egg Quality
Omega-3 fatty acids are essential for fertility, and most of us don’t get enough from diet alone. These healthy fats help:
✅ Reduce inflammation, which supports implantation
✅ Balance reproductive hormones
✅ Improve egg quality & blood flow to the ovaries
💡 What the science says:
Studies have found that higher Omega-3 levels were associated with improved embryo quality in women over 35.
🔹 My dosage: 2000mg daily of high-quality, mercury-free fish oil
4. Vitamin D – The Must-Have “Fertility Hormone”
Did you know that Vitamin D acts like a hormone in the body? Many women struggling with fertility are deficient in it!
✨ Benefits for fertility:
✅ Regulates reproductive hormones (FSH, AMH, estrogen)
✅ Supports healthy implantation & pregnancy maintenance
✅ Reduces miscarriage risk
💡 What the science says:
Studies show that Vitamin D deficiency is linked to lower pregnancy rates and higher miscarriage risk.
🔹 My dosage: 4000 IU of Vitamin D3 daily since I was deficient; please speak to your doctor about the right dose for you
5. Prenatal Vitamins – For Overall Fertility Support
I started taking a high-quality prenatal vitamin 3 months before I began trying to conceive.
✨ A good prenatal should include:
✅ Folic acid (or methylfolate) – Prevents birth defects & supports cell division
✅ Iron – Helps prevent anemia & supports a healthy uterine lining
✅ Choline & B-complex vitamins – Important for early fetal development
💡 What the science says:
When the right ingredients are included, prenatal vitamins help prepare our bodies for pregnancy and prevent tubal defects.
🔹 My choice: A high-quality prenatal with methylfolate (not folic acid), iron, and choline
6. NAC (N-Acetyl Cysteine) – For Egg Quality & Detox Support
NAC is a powerful antioxidant that helps reduce oxidative stress, which is a major cause of egg aging.
✨ Benefits for fertility:
✅ Supports egg health & protects against free radicals
✅ Improves insulin sensitivity (great for women with PCOS or blood sugar issues)
✅ May help prevent miscarriage by reducing inflammation
💡 What the science says:
One study found that NAC supplementation improved ovulation rates and pregnancy success in women with PCOS.
🔹 My dosage: 600 mg twice daily
7. Magnesium – The “Calm & Fertile” Mineral
Magnesium plays a role in hormone regulation, stress management, and egg health.
✨ Benefits for fertility:
✅ Supports progesterone production, which is essential for implantation
✅ Reduces stress & cortisol levels, which can interfere with conception
✅ Helps regulate insulin & blood sugar
💡 What the science says:
Studies show that Magnesium deficiency can negatively impact progesterone levels and overall reproductive health.
🔹 My dosage: 400mg of Magnesium Glycinate daily
8. Acai Berry – The Antioxidant Powerhouse for Egg Quality
One of the biggest challenges women over 35 face when trying to conceive is declining egg quality due to oxidative stress. That’s where Acai berry comes in!
Acai is a superfruit packed with antioxidants, specifically anthocyanins, which help protect eggs from free radical damage and improve overall reproductive health.
✨ Benefits for fertility:
✅ Rich in antioxidants to protect egg quality
✅ Supports ovarian function & blood flow to the uterus
✅ May improve fertility outcomes in women with low ovarian reserve
💡 What the science says:
Research conducted by the Colorado Center for Reproductive Medicine found that antioxidant therapy (including acai) helped improve egg quality and fertility in women with diminished ovarian reserve. More on Acai berry here.
🔹 My dosage: I took an acai berry supplement – 600 mg- twice per day.
Final Thoughts: What Worked for Me Can Work for You, Too!
I believe these supplements played a HUGE role in helping me conceive naturally at 41. But remember:
💡 We are all different. What worked for me might not be what you need.
💡 Consult your doctor before starting new supplements, especially if you have existing health conditions.
💡 Consistency is key. It took me a few months to see results, but it was 100% worth it!
Whether you’re trying to conceive naturally or with IVF, stay hopeful! 🌸 Your body is capable, your journey is unique, and your baby is worth the wait. 💕
Have you tried any of these supplements? Let me know in the comments—I’d love to hear your story! 😊✨